Will be driving back from Kansas City to Ankeny Later Saturday into Saturday evening. Is everything supposed to be through by then?
The worst regarding intensity of falling snow should be over, but I don't think everything will be done.
Currently, I'm thinking most of your route is just going to see a lot of rain, with minimal snow, probably going to snow around when you are coming back. I-80 from Atlantic west is probably where I would worry.
I don't think I-35 south should be that bad. Wet, maybe slushy, but common sense should get you through decently.