Milwaukee will be. No way that RPI stays sub 100.
A decent chance it'll drop under 100. Rest of Milwaukee's non-conference is unlikely to boost RPI: Montana State, Jacksonville, Western Illinois, at Belmont, Western Mich. If UWM runs the table there and wins A Lot in Horizon, number might stay fairly steady.
It's a micro-detail anyway, ISU's resume isn't going to succeed or fail based on that loss. Worst-case, it'll be a home defeat vs. a sub-150 RPI team. Plenty of chances to balance that with quality wins.