I always hate this for a couple different reasons.
#1 they're going to see plenty on film about tendencies. Does the LG struggle to block to his right? Does the RT have poor footwork that can be exploited? Can the OL handle twists and stunts or get into the right protections? Where do they most consistently get push? Is a certain receiver hesitant over the middle? Coaches are looking for matchups to schematically take advantage of. 3, 41, 3, 17, 17, 10. Even with a 41 point game we have averaged 15 points in Campbell's tenure against Iowa. Parker owns Campbell's offenses. Change the play caller but the principals are still the exact same. We're still a power running spread offense that will have all the same wrinkles basically any other power running spread offense has because almost everyone copies someone else.
#2 Both sides coaches for the most part have seen about everything. There isn't going to be some mystery wrinkle that comes out from either team they haven't seen before. It isn't like Campbell hired a new OC running the air raid. Even if he did they would just go back to the previous film of that coach's offense.
#3 Does the same principle apply for Iowa then? The outcome of their game was never in doubt. McNamara HAS to be more skilled than Petras. Was Ferentz just holding him back? Just having someone with any skill taking the snaps would automatically make their offense significantly different.