I think the most successful players to come from ISU to the NFL are on this current team. We've had some good ones over the years but Campbell already has one of the better ones in Montgomery in the league and there are a handful of guys on this year's team that could get drafted.
AJ Klein has had probably the best NFL career of any Cyclone so far. Going into his 9th season coming off probably his best statistical season of his career too. KO has had a nice career too and is right up there with him too. Lazzard may carve out a place on the list too if he keeps it up but other than those guys mentioned already Seneca, Sage, Jordan Carstens, James Reed, and Reggie Heyward are about the only former players with any kind of longevity in the league.