I know exactly the play you are talking about. Its a counter-type play designed to make defenses pay for "slow playing" the zone read. Team I've seen run it the best in the past is Northwestern. Also vs Tech's man coverage with the LB matching up on the RB, that's probably something ISU was probable trying to take advantage of as well and get the LB thinking.
RB comes across QB to take handoff, but then changes directions and goes back where he came from. Gets LB's moving and then the tackle/guard combo is supposed to pick him up with a pulling guard coming from the backside to kick out the DE who is "slow playing" the zone read. I love the thought behind it, but 2 problems. Back is coming to a complete stop in the backfield and running parallel to LOS too much, and the time I am thinking I saw it, the kickout guy got blown up by the DE and there was no hole anyway. A way we've run it in past is to send the RB all the way across and take the fake, then have the QB keep it and run up the hole. Need a qb that can run between the tackles to do that though, and it works better if you have a tackle from the backside and lead up and block the PSLB so you can take the G-T double team all the way to the backside LB.
I will draw up the play I think ISU was trying and try to get it on here. I'm not sure its exactly accurate but it is close. We were trying it early in the game if anyone has a clip.