As a former Sioux Falls resident, I have the following suggestions:
For Food:
Minerva's
Philips Ave Diner
Mama Enchilada
JL Beers (Burgers and Microbrew)
For Bars:
Copper Lounge (bit more refined)
Wiley's (Younger, fun)
Icon (Hipster)
TommyJacks (Townie)
Stogeez (Cigar)
Falls Landing (Hotel bar on the riverfront)
For Food:
Minerva's
Philips Ave Diner
Mama Enchilada
JL Beers (Burgers and Microbrew)
For Bars:
Copper Lounge (bit more refined)
Wiley's (Younger, fun)
Icon (Hipster)
TommyJacks (Townie)
Stogeez (Cigar)
Falls Landing (Hotel bar on the riverfront)