The 5* recruiting juggernauts will be gone. On the other hand Arizona is 8-3 this year. Utah is 7-4 this year, and they have been a very good team for the previous 5 seasons (9/10 wins except for the COVID year). These are not slouches.
If KU can beat Cinci next week, 8 Big 12 teams will finish with winning conference records. The bottom of the Big 12 was not good this year, and the better teams feasted on the bottom teams. I don't see any reason to exepct signficiant drop-offs at KSU, KU, OkSU, TT and WVU. So far this year, ISU is 1-4 against P5 teams with winning conference records.
Apart from a philosophy change on offense to where ISU adapts early and tries to score more in the first half if they can't run the ball, I think ISU's ceiling is 7-8 wins. If there is no change, Campbell is not going to "out-Iowa" Kirk, so that game will continue to be a loss. More Ohio-type losses are going to sneak in with the other two "easy" non-con games if ISU allows those teams to hang around into the second half. Same in the Big 12. The conference is just too balanced to give up a half of football before the offense starts looking for other means to score if the primary pound-it-up the middle plan gets stopped.