Honestly, I think going west might not be a bad idea for ISU. Neither school has a commanding grip on fans in the western half of the state (Nebraska has more of a presence, though), which is a lot different than trying to go into the lion's den, so to speak.
While in thought I'm totally with you on the idea of securing more Western Iowans (and it would be great to keep people from cheering for Nebraska.) Besides not being as populated, I don't think these type of things are really there to "sway" fans one way or the other. It's more for where your fans already are. I don't think ISU in CR would be any more or less "going into the lion's den" than Iowa in DSM. I don't think Iowa's spring practice was competing for fans with ISU's Spring Game on any significant level.